Shyh-Chyi Kuo  1 and Yukon Chou1

1Electronics Research & Service Organization Industrial Technology Research Institute Jhudong, Taiwan 310, R.O.C.


Received: January 15, 2004
Accepted: February 18, 2004
Publication Date: June 1, 2004

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This paper presents a novel method to fabricate polymeric hollow microneedles with sharp tips by a proprietary photolithography and molding process. This process can be employed to fabricate a multi-layer structure that consists of a microchannel layer, a supporting layer and many polymeric hollow out-of-plane microneedles on the supporting layer. The structure was fabricated monolithically, and won’t be out of shape after high temperature/high pressure vapor test. It can be used for biomedical applications such as drug delivery, blood sensing and printing tip array. We also determine the microneedles for blood extraction by numerical simulation. Furthermore, this array of needles was coated with polydimethylsiloxane (PDMS) to make an inverse mold.

Keywords: Microneedle, Micromolding


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