Journal of Applied Science and Engineering

Published by Tamkang University Press

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Material Engineering Mechanical Engineering

Khola Ikram1, Syed Maaz Hasan1This email address is being protected from spambots. You need JavaScript enabled to view it., Ch Abdullah1, M Zulfiqar1, Emad Uddin1, Zaib Ali1, and M. Sajid2

1Department of Mechanical Engineering, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), H-12, Islamabad, Pakistan

2School of Mechanical and Materials Engineering, University College Dublin, Dublin, Ireland

 

 

Received: August 16, 2024
Accepted: October 4, 2024
Publication Date: November 4, 2024

 Copyright The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.


Download Citation: ||https://doi.org/10.6180/jase.202508_28(8).0006  


The curvature of microchannels significantly influences the direction and amplitude of secondary flow, impact ing particle sorting efficiency. Using an inertia-based microchannel model for particle sorting, a detailed flow characterization analysis was done to identify particle sorting and promote standards methods in the microflu idics field. Bends of various angles have numerous uses in microfluidics, and it is essential to comprehend the f lowbehavior in these microchannels. This work represents the results of a microchannel analysis with various micro-bend angles. Four microchannel designs were studied with outlet angles of 45◦,60◦,90◦, and straight channels. Microchannel was fabricated through SLA 3d printing and laser cutting. To investigate the influence of flow-related parameters on systems performance, testing was conducted using 10 & 20 µm, 20 & 60 µm, and 40 &60 µmsizedparticles and flow rates of 50-250 µL/min to stimulate red and white blood cells. Furthermore, imaging was done using a microscope, and postprocessing was done through MATLAB Image Processing. This study reveals that a detailed investigation of particle sorting is necessary to produce consistent test techniques for microfluidic devices to enhance medical diagnostic field performance and promote advancement in the biomedical industry.

 


Keywords: Particle sorting; Microfluidics; SLA printing; Laser cutting; Microchannels


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