Journal of Applied Science and Engineering

Published by Tamkang University Press

1.30

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2.10

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C. T. Wang This email address is being protected from spambots. You need JavaScript enabled to view it.1 and Y. C. Hu1

1Department of Mechanical and Electro-Mechanical Engineering, National I-Lan University, I-Lan, Taiwan 260, R.O.C.


 

Received: June 16, 2009
Accepted: May 6, 2010
Publication Date: December 1, 2010

Download Citation: ||https://doi.org/10.6180/jase.2010.13.4.04  


ABSTRACT


Mixing of binary or multi-component fluid streams is difficult in microchannels because they rely on diffusion during a limited mixing length. Therefore, obstacles applied and placed in the microchannel need to be used to try to disrupt the flow and reduce the diffusion path. In this study, finding a better layout for such obstacles embedded in Y-type microchannel is important to enhance flow mixing and will be executed at Reynolds numbers ranging from 0.5 to 60. These parameters of layout, such as number, horizontal spacing distance and angle of arrangement for cylinders embedded in the channel, as well as an inlet Reynolds number ratio, are worthy of study because they directly influence mixing and have rarely been previously addressed. The useful numerical results confirmed by our experiment will be addressed in this paper. Generally speaking, a larger number of cylinders, and a smaller horizontal spacing distance between them, normally correspond to a stronger flow mixing. In the case studied herein, five cylinders, arranged in a V with an angle of 90° at the base of the V, and the horizontal spacing distance between pairs of cylinders of 100 μm, is a better choice for providing enhanced flow mixing. In addition, the Reynolds number ratio of ten is suggested because it induces a more intensive lateral convection and produces enhanced flow mixing. Placing obstacles or textures in the microchannel is a significant method for mixing in microfluidic devices because of its simple prototype and ease of fabrication, and the results could provide useful information for future optimal design of these devices.


Keywords: Y-Type Microchannel, Obstacle, Flow Mixing, Optimal Design


REFERENCES


  1. [1]Yahng J-S, Jeoung S-C, Choi D-S, Cho D, Kim J-H, Choi H-M, Park J-S. Fabrication of Microfluidic Devices by Using a Femtosecond Laser Micromachining Technique and μ-PIV Studies on its Fluid Dynamics. J Korean Phys Soc. 2005; 47(6):977-981.
  2. [2]Auroux P-A, Iossifidis D, Reyes D-R, Manz A. Micro Total Analysis Systems. 2. Analytical Standard Operations and Applications. Anal Chem. 2002;74(12):2637-2652.
  3. [3]Reyes D-R, Iossifidis D, Auroux P-A, Manz A. Micro Total Analysis Systems. 1. Introduction, Theory, and Technology. Anal Chem. 2002;74(12):2623-2636.
  4. [4]Vilkner T, Janasek D, Manz A. Micro Total Analysis Systems. Recent Developments. Anal Chem. 2004;76(12):3373-3386.
  5. [5]Cha N-G, Park C-H, Lim H-W, Lim J-G. J Korean Phys Soc. 2005;47:S530.
  6. [6]Jakeway S-C, de Mello A-J, Russell E-L. Miniaturized Total Analysis Systems for Biological Analysis. Fresenius J Anal Chem. 2000;366:525-539.
  7. [7]Nguyen N-T, Wu Z. J. Micromixers—a Review. Micromech. Microeng. 2005;15:R1-R16.
  8. [8]Deshmukh A-A, Liepmann D, Pisano A-P. Continuous Micromixer with Pulsatile Micropumps. IEEE Workshop on Solid State Sensor and Actuators, Hilton Head Island, SC, 2000;73-76.
  9. [9]Fujii T, Sando Y, Higashino K, Fujii Y. A Plug and Play Microfluidic Device. Lab Chip. 2003;3:193-197.
  10. [10]Jacobson S-C, Mcknight T-E, Ramsey J-M. Microfluidic Devices for Electrokinetically Driven Parallel and Serial Mixing. Anal Chem. 1999;71(20):4455-4459.
  11. [11]Oddy M-H, Santiago J-G, Mikkelsen J-C. Electrokinetic Instability Micromixing. Anal Chem. 2001;73(24): 5822-5832.
  12. [12]Rife J-C, Bell M-I, Horwitz J-S, Kabler M-N, Auyeung RCY, Kim W-J. Miniature Valveless Ultrasonic Pumps and Mixers. Sens Actuat. A:Phys. 2000; 86:135-140.
  13. [13]Yang Z, Goto H, Matsumoto M, Maeda R. Active Micromixer for Microfluidic Systems Using Lead-Zirconate-Titanate(PZT)-Generated Ultrasonic Vibration. Electrophoresis. 2000;21:116-119.
  14. [14]Yasuda K. Non-Destructive, Non-Contact Handling Method for Biomaterials in Micro-Chamber by Ultrasound. Sens Actuat B-Chem. 2000;64:128-135.
  15. [15]Bau H-H, Zhong J-H, Yi M-Q. A Minute Magneto Hydrodynamic (MHD) Mixer. Sens Actuat B-Chem. 2001;79:207-215.
  16. [16]Johnes S-W, Aref H. Chaotic Advection in Pulsed Source-Sink Systems. Phys Fluids. 1998; 31: 469-485.
  17. [17]Johnson T-J, Ross D, Locascio L-E. Rapid Microfluidic Mixing. Anal Chem. 2002;74(1):45-51.
  18. [18]Liu R-H, Stremler M-A, Sharp K-V, Olsen M-G, Santiago J-G, Adrian R-J, Aref H, Beebe D-J. Passive Mixing in a Three-Dimensional Serpentine Microchannel. J Microelectromech Systems. 2000;9(2):190-197.
  19. [19]Mengeaud V, Josserand J, Girault H-H. Mixing Processes in a Zigzag Microchannel: Finite Element Simulations and Optical Study. Anal Chem. 2002;74(16):4279-4286.
  20. [20]Stroock A-D, Dertinger SKW, Ajdari A, Mezic I, Stone H-A, Whitesides G-M. Chaotic Mixer for Microchannels. Sci. 2002;295(5555);647-651.
  21. [21]Wang H-Z, Iovenitti P, Harvey E, Masood S. Optimizing Layout of Obstacles for Enhanced Mixing in Microchannels. Smart Mate Struct. 2002;11:662-667.
  22. [22]Wang H-Z, Iovenitti P, Harvey E, Masood S. Numerical Investigation of Mixing in Microchannels with Patterned Grooves. J Micromech Microeng. 2003;13(6):801-808.
  23. [23]Kim, T.-A., Kim, Y.-J., Effects of obstacles on the mixing performance in microchannels, Proceedings of the 5th International Conference on Nanochannels, Microchannels and Minichannels, ICNMM2007, 2007:709-716.
  24. [24]Hinsmann P, Frank J, Svasek P, Harasek M, Lendl B. Design, Simulation and Application of a New Micromixing Device for Time Resolved Infrared Spectroscopy of Chemical Reactions in Solution. Lab Chip. 2001;1:16-21.
  25. [25]Ismagilov R-F, Stroock A-D, Kenis PJA, Whitesides G, Stone H-A. Experimental and Theoretical Scaling Laws for Transverse Diffusive Broadening in Two-Phase Laminar Flows in Microchannels. Appl Phy. Lett. 2000;76:2376-2378.
  26. [26]Kamholz A-E, Yager P. Molecular Diffusive Scaling Laws in Pressure-Driven Microfluidic Channels: Deviation From One-Dimensional Einstein Approximations. Sens Actuat B-Chem. 2002;82:117-121.
  27. [27]Lim DSW, Shelby J-P, Kuo J-S, Chiu D-T. Dynamic Formation of Ring-Shaped Patterns of Colloidal Particles in Microfluidic Systems. Appl Phys Lett. 2003;83:1145-1147.
  28. [28]Wu Z-G, Nguyen N-T, Huang X-Y. Nonlinear Diffusive Mixing in Microchannels: Theory and Experiments. J. Micromech. Microeng. 2004;14:604-611.
  29. [29]Maeng J-S, Cho I-D, Kim B-J. Prediction of Degree of Mixing for Insoluble Solution with Vortex Index in a Passive Micromixer.Trans KSME B. 2005;29(2):232-238.
  30. [30]Wang, H., Iovenitti, P., Harvey, E., and Masood, S. Mixing of liquids using obstacles in microchannel. proceedings SPIE, BioMEMS and Smart Nanostructures. 2001;4590:204-212.