{"id":8772,"date":"2026-06-29T17:09:09","date_gmt":"2026-06-29T09:09:09","guid":{"rendered":"\/jase\/?post_type=tkuisotope&#038;p=8772"},"modified":"2026-06-29T18:35:26","modified_gmt":"2026-06-29T10:35:26","slug":"jase-202610-33-025","status":"publish","type":"tkuisotope","link":"\/jase\/?tkuisotope=jase-202610-33-025","title":{"rendered":"A Functional Connectivity-Based Deep Belief Network for ADHD Detection from Resting-State fMRI Data"},"content":{"rendered":"\n<div class=\"wp-block-tkuwpbs5-bs5-row row article-info\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=807\" data-type=\"page\" data-id=\"807\">2026<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder-open\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=7886\" data-type=\"page\" data-id=\"7886\">Volume 33<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-6 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div dv_publish\" data-aos=\"normal\"><div class=\"wp-block-post-date\"><time datetime=\"2026-06-29T17:09:09+08:00\">2026-06-29<\/time><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-row row\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-5 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div au-ol\" data-aos=\"normal\">\n<p>Hongmei Li<sup>1<\/sup> and Yang Chen<sup>2<\/sup><a href=\"mailto:jessica_cy@163.com\"><i class=\"fa fa-envelope\"><\/i><\/a><\/p>\n\n\n\n<p style=\"font-size:14px\"><sup>1<\/sup>Information Engineering College, Hunan Applied Technology University, Changde 415000, Hunan, China<\/p>\n\n\n\n<p style=\"font-size:14px\"><sup>2<\/sup>Anhui Xinhua University, Hefei 230000, Anhui, China<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div\" style=\"margin-top:var(--wp--preset--spacing--40)\" data-aos=\"normal\">\n<p>Received: May 21, 2025<br>Accepted:&nbsp;January 18, 2026<br>Publication Date:&nbsp;June 29, 2026<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-7 align-self-start clk=\u5716\u7247\"><img decoding=\"async\" src=\"\/jase\/wp-content\/uploads\/2026\/06\/33_025.jpg\" class=\"img-fluid img-fluid mx-auto d-block\" alt=\"\u4e0a\u50b3\u5716\u7247\">\n\n\n<p class=\"has-text-align-center\">Each block within the feature extraction unit is&nbsp;applied&nbsp;to&nbsp;every&nbsp;90 -region. All networks have&nbsp;similar&nbsp;weights<\/p>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-small-font-size\"><i class=\"fab fa-creative-commons\"><\/i>&nbsp;<strong>Copyright&nbsp;<\/strong>The Author(s). This is an open access article distributed under the terms of the&nbsp;<a rel=\"noreferrer noopener\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\">Creative Commons Attribution&nbsp;License (CC BY 4.0)<\/a>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.<\/p>\n\n\n\n<p>Download Citation:\u00a0 <a href=\"\/jase\/wp-content\/uploads\/2026\/06\/V33.0025.txt\" data-type=\"attachment\" data-id=\"8787\" target=\"_blank\" rel=\"noreferrer noopener\">BibTeX <\/a>| <a rel=\"noreferrer noopener\" href=\"http:\/\/dx.doi.org\/10.6180\/jase.202610_33.025\" target=\"_blank\">http:\/\/dx.doi.org\/10.6180\/jase.202610_33.025<\/a>\u00a0\u00a0<\/p>\n\n\n\n<p class=\"btn btn-primary article-btn\"><a href=\"\/jase\/wp-content\/uploads\/2026\/06\/025_2025_0445_V33.pdf\" data-type=\"attachment\" data-id=\"8776\" target=\"_blank\" rel=\"noreferrer noopener\">Download PDF<\/a><\/p>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Resting state fMRI has emerged as a popular neuroimaging tool for the automated identification and classification of brain disorders. Among such disorders, ADHD (attention deficit hyperactivity disorder), which is a disorder affecting children, is ill-understood regarding the causative factors, and its diagnosis is mainly based on behavioral evaluations. Here, a deep learning (DL) direct tactic for ADHD recognition is introduced. Our proposed architecture is structured into three main components: (1) a feature extraction unit, (2) a functional connectivity unit, and (3) a three-layer deep belief network. The scheme receives preprocessed time-series fMRI signals as input and produces a diagnostic output. It is trained in a direct manner utilizing backprop agation. The experimental findings obtained from the publicly accessible ADHD-200 database indicate that this novel approach surpasses the prior innovative tactics. The recommended method achieved accuracy rates of 91.84%, 91.08%,  87.73%, and 89.62% for PU, KKI, NYU, and NI databases from the ADHD-200 database. On average, the recommended method achieved an accuracy of 90.06%, a specificity of 88.37%, an F1-score of 89.93%, and a sensitivity of 91.55% in ADHD recognition from fMRI scans. Our findings demonstrate significant advancements in categorization performance compared to existing tactics, highlighting both the utility of functional connectivity as a biomarker and the effectiveness of DL in neuroimaging contexts.<\/p>\n\n\n\n<p><em>Keywords:&nbsp;fMRI; ADHD; DL;functional connectivity; deep belief network<\/em><\/p>\n\n\n\n<div style=\"height:2rem\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div ref_ol\" data-aos=\"normal\">\n<div class=\"container\">\n<div id=\"model-response-message-contentr_442dd220420d5a90\" class=\"markdown markdown-main-panel stronger enable-updated-hr-color\" dir=\"ltr\" aria-live=\"polite\" aria-busy=\"false\">\n<div class=\"container\">\n<div id=\"model-response-message-contentr_bb65d10f6a8ddbc4\" class=\"markdown markdown-main-panel stronger enable-updated-hr-color\" dir=\"ltr\" aria-live=\"polite\" aria-busy=\"false\">\n<ol>\n<li data-path-to-node=\"0\">[1] C. Nash, R. Nair, and S. M. Naqvi, (2024) \u201cInsights into detecting adult ADHD symptoms through advanced dual-stream machine learning\u201d IEEE Transactions on Neural Systems and Rehabilitation Engineering 32: 3378\u20133387. DOI: 10.1109\/TNSRE.2024.3450848.<\/li>\n<li data-path-to-node=\"0\">[2] M. R. Mohammadi, A. Khaleghi, K. Shahi, and H. Zarafshan, (2023) \u201cAttention deficit hyperactivity disorder: behavioral or neuro-developmental disorder? testing the hitop framework using machine learning methods\u201d Journal of Iranian Medical Council: DOI: 10.18502\/jimc.v6i4.13444.<\/li>\n<li data-path-to-node=\"0\">[3] G. Ayano, S. Demelash, Y. Gizachew, L. Tsegay, and R. Alati, (2023) \u201cThe global prevalence of attention deficit hyperactivity disorder in children and adolescents: An umbrella review of meta-analyses\u201d Journal of affective disorders 339: 860\u2013866. DOI: 10.1016\/j.jad.2023.07.071.<\/li>\n<li data-path-to-node=\"0\">[4] M.-R. Mohammadi, H. Zarafshan, A. Khaleghi, N. Ahmadi, Z. 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DOI: 10.1038\/s41386-022-01408-z.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"author":3,"template":"wp-custom-template-detail-4-aricles","meta":{"_uag_custom_page_level_css":""},"categories":[12,1483,6],"tags":[1639],"acf":[],"uagb_featured_image_src":[],"uagb_author_info":{"display_name":"\u6797\u923a\u6db5","author_link":"\/jase\/?author=3"},"uagb_comment_info":0,"uagb_excerpt":"&nbsp;Copyright&nbsp;The Author(s). This is an open access article distributed under the terms of the&nbsp;Creative Commons Attribution&nbsp;License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited. Download Citation:\u00a0 BibTeX | http:\/\/dx.doi.org\/10.6180\/jase.202610_33.025\u00a0\u00a0 Download PDF Resting state fMRI has emerged as a popular neuroimaging tool for&hellip;","_links":{"self":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope\/8772"}],"collection":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope"}],"about":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/types\/tkuisotope"}],"author":[{"embeddable":true,"href":"\/jase\/index.php?rest_route=\/wp\/v2\/users\/3"}],"wp:attachment":[{"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8772"},{"taxonomy":"post_tag","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}