{"id":838,"date":"2026-03-08T00:51:40","date_gmt":"2026-03-07T16:51:40","guid":{"rendered":"https:\/\/iweb20wp-b205b.url.tku.edu.tw\/jase\/?post_type=tkuisotope&#038;p=838"},"modified":"2026-03-18T14:17:30","modified_gmt":"2026-03-18T06:17:30","slug":"segnet-based-framework-for-robust-lung-tumor-segmentation-from-pet-ct-scans","status":"publish","type":"tkuisotope","link":"\/jase\/?tkuisotope=segnet-based-framework-for-robust-lung-tumor-segmentation-from-pet-ct-scans","title":{"rendered":"SegNet-Based Framework for Robust Lung Tumor Segmentation from PET\/CT Scans"},"content":{"rendered":"\n<div class=\"wp-block-tkuwpbs5-bs5-row row article-info\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=807\" data-type=\"page\" data-id=\"807\">2026<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder-open\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=817\" data-type=\"page\" data-id=\"817\">Volume 30<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-6 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div dv_publish\" data-aos=\"normal\"><div class=\"wp-block-post-date\"><time datetime=\"2026-03-08T00:51:40+08:00\">2026-03-08<\/time><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-row row\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-5 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div au-ol\" data-aos=\"normal\">\n<p>Yessine Amri<sup>1<\/sup><a href=\"mailto: amri.yessine@yahoo.com\"><i class=\"fa fa-envelope\"><\/i><\/a>, Amine Ben Slama<sup>2<\/sup>, and Zouhair Mbarki<sup>3<\/sup><\/p>\n\n\n\n<p style=\"font-size:14px\"><sup>1<\/sup>Biochemistry Laboratory, Bechir Hamza Children\u2019s Hospital, Tunis, 1007, Tunisia<\/p>\n\n\n\n<p style=\"font-size:14px\"><sup>2<\/sup>Research Laboratory of Biophysics and Medical Technologies LRBTM (LR13ES07), Higher Institute of Medical Technologies of Tunis (ISTMT), University of Tunis El Manar, Tunis,1006, Tunisia<\/p>\n\n\n\n<p style=\"font-size:14px\"><sup>3<\/sup>RIFTSI Research Laboratory, ENSIT, University of Tunis, Tunis, 1008, Tunisia<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div\" style=\"margin-top:var(--wp--preset--spacing--40)\" data-aos=\"normal\">\n<p>Received:\u00a0July 25, 2025<br>Accepted:\u00a0October 12, 2025<br>Publication Date:\u00a0March 8, 2026<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-7 align-self-start\"><img decoding=\"async\" src=\"\/jase\/wp-content\/uploads\/2026\/03\/30_008.jpg\" class=\"img-fluid img-fluid mx-auto d-block\" alt=\"\u4e0a\u50b3\u5716\u7247\">\n\n\n<p class=\"has-text-align-center img_caption\">Seg-Net model.<\/p>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-small-font-size\"><i class=\"fab fa-creative-commons\"><\/i>&nbsp;<strong>Copyright&nbsp;<\/strong>The Author(s). This is an open access article distributed under the terms of the&nbsp;<a rel=\"noreferrer noopener\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\">Creative Commons Attribution&nbsp;License (CC BY 4.0)<\/a>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.<\/p>\n\n\n\n<p>Download Citation:\u00a0 <a rel=\"noreferrer noopener\" href=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" data-type=\"link\" data-id=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" target=\"_blank\">RIS<\/a> | <a rel=\"noreferrer noopener\" href=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" data-type=\"link\" data-id=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" target=\"_blank\">BibTeX <\/a>| <a href=\"http:\/\/dx.doi.org\/10.6180\/jase.202607_30.008\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/dx.doi.org\/10.6180\/jase.202607_30.008<\/a>\u00a0\u00a0<\/p>\n\n\n\n<p class=\"btn btn-primary article-btn\"><a href=\"\/jase\/wp-content\/uploads\/2026\/03\/008_2025_0938.pdf\" data-type=\"attachment\" data-id=\"894\" target=\"_blank\" rel=\"noreferrer noopener\">Download PDF<\/a><\/p>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Lung cancer remains one of the leading causes of cancer-related mortality worldwide, often due to latestage diagnosis and the complexity of tumor localization in thoracic imaging. Accurate and automated segmentation of lung tumors from PET\/CT images is essential for early diagnosis, treatment planning, and outcome monitoring. Manual segmentation is time-consuming and prone to observer variability, underscoring the need for reliable deep learning-based solutions. This study proposes an automated lung tumor segmentation framework using the SegNet architecture, a deep encoder-decoder convolutional neural network. A dataset of 1, 425PET\/CT images, manually annotated by expert radiologists, was utilized. Data augmentation techniques were applied to improve generalization. SegNet was trained to perform pixel-wise binary classification, and its performance was benchmarked against the widely used U-Net model. Evaluation metrics included Accuracy, Recall, Dice coefficient, and Intersection over Union (IoU).The proposed SegNet model achieved strong segmentation performance across independent experiments. Average results were: Accuracy of 92.24% \u00b1 1.42, Recall of 94.02% \u00b1 1.287, Dice coefficient of 93.47% \u00b1 1.4, and IoU of 93.03% \u00b1 1.2. Compared to U-Net (Dice: 92.18% \u00b1 1.081, IoU: 91.70% \u00b1 1.287 ), SegNet demonstrated improved spatial boundary accuracy, particularly for tumors located near complex anatomical structures. Statistical tests confirmed the significance of the performance difference ( p &lt; 0.05 ). The SegNet-based model provides accurate and robust segmentation of lung tumors in PET\/CT images, outperforming U-Net under the same conditions. Its use of max-pooling indices enhances spatial precision, making it well-suited for clinical applications. Future work will explore 3D extensions, multi-class segmentation, and multi-center validation to enhance its applicability in real-world diagnostic workflows.<\/p>\n\n\n\n<p><em>Keywords:\u00a0Lung tumor, PET\/CT, Deep learning, SegNet, Medical image segmentation, U-Net<\/em><\/p>\n\n\n\n<div style=\"height:2rem\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div ref_ol\" data-aos=\"normal\">\n<ol>\n<li>[1] B. Le Goff, J.-M. Berthelot, and Y. Maugars, (2015) \u201c\u00c9chographie du thorax ant\u00e9rieur [Ultrasound of the anterior thorax]&#8221; Revue du Rhumatisme Monographies 82(2): 83\u201387. DOI: 10.1016\/j.monrhu.2015.02.005.<\/li>\n<li>[2] C. Jani, D. C. Marshall, H. Singh, R. Goodall, J. Shalhoub, O. Al Omari, and C. C. Thomson, (2021) \u201cLung cancer mortality in Europe and the USA between 2000 and 2017: An observational analysis&#8221; ERJ Open Research 7(4): DOI: 10.1183\/23120541.00311-2021.<\/li>\n<li>[3] P. B. 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This is an open access article distributed under the terms of the&nbsp;Creative Commons Attribution&nbsp;License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited. Download Citation:\u00a0 RIS | BibTeX | http:\/\/dx.doi.org\/10.6180\/jase.202607_30.008\u00a0\u00a0 Download PDF Lung cancer remains one of the leading causes of&hellip;","_links":{"self":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope\/838"}],"collection":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope"}],"about":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/types\/tkuisotope"}],"author":[{"embeddable":true,"href":"\/jase\/index.php?rest_route=\/wp\/v2\/users\/3"}],"wp:attachment":[{"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=838"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=838"},{"taxonomy":"post_tag","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}