{"id":836,"date":"2026-03-08T00:50:19","date_gmt":"2026-03-07T16:50:19","guid":{"rendered":"https:\/\/iweb20wp-b205b.url.tku.edu.tw\/jase\/?post_type=tkuisotope&#038;p=836"},"modified":"2026-03-18T13:26:30","modified_gmt":"2026-03-18T05:26:30","slug":"trustworthy-retinopathy-of-prematurity-diagnosis-using-explainable-vision-language-model","status":"publish","type":"tkuisotope","link":"\/jase\/?tkuisotope=trustworthy-retinopathy-of-prematurity-diagnosis-using-explainable-vision-language-model","title":{"rendered":"Trustworthy retinopathy of prematurity diagnosis using explainable vision-language model"},"content":{"rendered":"\n<div class=\"wp-block-tkuwpbs5-bs5-row row article-info\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=807\" data-type=\"page\" data-id=\"807\">2026<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-3 align-self-start\">\n<p><i class=\"fa fa-folder-open\" aria-hidden=\"true\"><\/i>&nbsp;<a href=\"\/jase\/?page_id=817\" data-type=\"page\" data-id=\"817\">Volume 30<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-6 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div dv_publish\" data-aos=\"normal\"><div class=\"wp-block-post-date\"><time datetime=\"2026-03-08T00:50:19+08:00\">2026-03-08<\/time><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-row row\">\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-5 align-self-start\">\n<div class=\"wp-block-tkuwpbs5-bs5-div au-ol\" data-aos=\"normal\">\n<p>Hikmat Z. Neima<a href=\"mailto: hikmat.taher@uobasrah.edu.iq\"><i class=\"fa fa-envelope\"><\/i><\/a>, Rana M. Ghadban, and Mohamed A. Abdulhamed<\/p>\n\n\n\n<p style=\"font-size:14px\">College of CSIT, University of Basrah, Basrah 61004, Iraq<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div\" style=\"margin-top:var(--wp--preset--spacing--40)\" data-aos=\"normal\">\n<p>Received:\u00a0August 28, 2025<br>Accepted:\u00a0November 8, 2025<br>Publication Date:\u00a0March 8, 2026<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-column col-md-7 align-self-start\"><img decoding=\"async\" src=\"\/jase\/wp-content\/uploads\/2026\/03\/30_006.jpg\" class=\"img-fluid img-fluid mx-auto d-block\" alt=\"\u4e0a\u50b3\u5716\u7247\">\n\n\n<p class=\"has-text-align-center img_caption\">Visual chart for comparison of AUC performance<\/p>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-small-font-size\"><i class=\"fab fa-creative-commons\"><\/i>&nbsp;<strong>Copyright&nbsp;<\/strong>The Author(s). This is an open access article distributed under the terms of the&nbsp;<a rel=\"noreferrer noopener\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\" target=\"_blank\">Creative Commons Attribution&nbsp;License (CC BY 4.0)<\/a>, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.<\/p>\n\n\n\n<p>Download Citation:\u00a0 <a rel=\"noreferrer noopener\" href=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" data-type=\"link\" data-id=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" target=\"_blank\">RIS<\/a> | <a rel=\"noreferrer noopener\" href=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" data-type=\"link\" data-id=\"\/jase\/wp-content\/uploads\/2026\/01\/jase-202509-28-09-0006.pdf\" target=\"_blank\">BibTeX <\/a>| <a href=\"http:\/\/dx.doi.org\/10.6180\/jase.202607_30.006\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/dx.doi.org\/10.6180\/jase.202607_30.006<\/a>\u00a0\u00a0<\/p>\n\n\n\n<p class=\"btn btn-primary article-btn\"><a href=\"\/jase\/wp-content\/uploads\/2026\/03\/006_2025_1159.pdf\" data-type=\"attachment\" data-id=\"892\" target=\"_blank\" rel=\"noreferrer noopener\">Download PDF<\/a><\/p>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Retinopathy of Prematurity (ROP) remains one of the leading causes of preventable childhood blindness, particularly in low-resource settings where specialist access is limited. Although deep learning has improved automated ROP detection, most existing models rely solely on retinal images and function as opaque black boxes, limiting clinical trust and realworld adoption. This study proposes a robust and trustworthy ROP diagnosis framework that combines Vision-Language Modeling (VLM) and Explainable AI. The pipeline fuses high-resolution wide-field retinal fundus images with neonatal NICU text records using a lightweight Vision Transformer, a clinical text encoder, and a neuro-symbolic reasoning layer for human-in-the-loop corrections. A key technical enhancement applies Weighted-Fuzzy Histogram Equalization (WFHE) to boost local vascular contrast while avoiding artifacts, outperforming Contrast Limited Adaptive Histogram Equalization CLAHE in highlighting subtle pathological cues. Evaluations on benchmark ROP datasets, paired with semi-structured NICU reports, demonstrate that the multimodal system improves diagnostic AUC by 7-9 % compared to image-only baselines, and delivers dual explanations through Grad-CAM heatmaps and SHAP token-level attributions. Structured clinician feedback confirms that the system\u2019s explanations align with expert annotations and improve interpretability and trust. This framework demonstrates that integrating WFHE, Vision-Language fusion, and multi-level explainability can enable transparent, deployable AI for equitable neonatal vision care.<\/p>\n\n\n\n<p><em>Keywords: Multimodal fusion; Neonatal retinal screening; Neuro-symbolic reasoning; Weighted-Fuzzy Histogram Equalization (WFHE)<\/em><\/p>\n\n\n\n<div style=\"height:2rem\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-tkuwpbs5-bs5-div ref_ol\" data-aos=\"normal\">\n<ol>\n<li>[1] S. Wang, J. Liu, X. Zhang, Y. Liu, J. Li, H. Wang, X. 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Download Citation:\u00a0 RIS | BibTeX | http:\/\/dx.doi.org\/10.6180\/jase.202607_30.006\u00a0\u00a0 Download PDF Retinopathy of Prematurity (ROP) remains one of the leading&hellip;","_links":{"self":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope\/836"}],"collection":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/tkuisotope"}],"about":[{"href":"\/jase\/index.php?rest_route=\/wp\/v2\/types\/tkuisotope"}],"author":[{"embeddable":true,"href":"\/jase\/index.php?rest_route=\/wp\/v2\/users\/3"}],"wp:attachment":[{"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=836"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=836"},{"taxonomy":"post_tag","embeddable":true,"href":"\/jase\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=836"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}